What Is Oral Cancer ?
Oral cancer is cancer that develops in the tissues of the mouth or throat. It belongs to a larger group of cancers called head and neck cancers. Most develop in the squamous cells found in your mouth, tongue, and lips.
More than 49,000 cases of oral cancer are diagnosed each year in the United States, occurring most often in people over 40 years old. Oral cancers are most often discovered after they’ve spread to the lymph nodes of the neck. Early detection is key to surviving oral cancer. Learn about what raises your risk, its stages, and more.
Types of oral cancers
Oral cancers include cancers of the:
- lips.
- tongue.
- the inner lining of the cheek.
- gums.
- the floor of the mouth.
- hard and soft palate.
Your dentist is often the first healthcare provider to notice signs of oral cancer. Getting biannual dental checkups can keep your dentist up to date on the health of your mouth.
Risk factors for developing oral cancer
One of the biggest risk factors for oral cancer is tobacco use. This includes smoking cigarettes, cigars, and pipes, as well as chewing tobacco.
People who consume large amounts of alcohol and tobacco are at even greater risk, especially when both products are used on a regular basis.
Other risk factors include:
- human papillomavirus (HPV) infection.
- chronic facial sun exposure.
- a previous diagnosis of oral cancer.
- a family history of oral or other types of cancer.
- a weakened immune system.
- poor nutrition.
- genetic syndromes.
- being male.
What are symptoms of oral cancer?
Symptoms of oral cancer include:
- a sore on your lip or mouth that won’t heal.
- a mass or growth anywhere in your mouth.
- bleeding from your mouth.
- loose teeth.
- pain or difficulty swallowing.
- trouble wearing dentures.
- a lump in your neck.
- an earache that won’t go away.
- dramatic weight loss.
- lower lip, face, neck, or chin numbness.
- white, red and white, or red patches in or on your mouth or lips.
- a sore throat.
- jaw pain or stiffness.
- tongue pain.
How is oral cancer diagnosed?
First, your doctor or dentist will perform a physical exam. This includes closely examining the roof and floor of your mouth, the back of your throat, tongue, and cheeks, and the lymph nodes in your neck. If your doctor cannot determine why you’re having your symptoms, you may be referred to an ear, nose, and throat (ENT) specialist.
If your doctor finds any tumours, growths, or suspicious lesions, they’ll perform a brush biopsy or a tissue biopsy. A brush biopsy is a painless test that collects cells from the tumour by brushing them onto a slide. A tissue biopsy involves removing a piece of the tissue so it can be examined under a microscope for cancerous cells.
In addition, your doctor may perform one or more of the following tests:
- X-rays to see if cancer cells have spread to the jaw, chest, or lungs.
- a CT scan to reveal any tumours in your mouth, throat, neck, lungs, or elsewhere in your body.
- a PET scan to determine if cancer has travelled to lymph nodes or other organs.
- an MRI scan to show a more accurate image of the head and neck, and determine the extent or stage of cancer.
- an endoscopy to examine the nasal passages, sinuses, inner throat, windpipe, and trachea.
What are the stages of oral cancer?
There are four stages of oral cancer.
- Stage 1: The tumour is 2 centimetres (cm) or smaller, and cancer hasn’t spread to the lymph nodes.
- Stage 2: The tumour is between 2-4 cm, and cancer cells haven’t spread to the lymph nodes.
- Stage 3: The tumour is either larger than 4 cm and hasn’t spread to the lymph nodes, or is any size and has spread to one lymph node, but not to other parts of the body.
- Stage 4: Tumors are any size and the cancer cells have spread to nearby tissues, the lymph nodes, or other parts of the body.
According to the National Cancer Institute, the five-year survival rates for oral cavity and pharynx cancers are as follows:
- 83 percent, for localized cancer (that hasn’t spread.
- 64 percent, for cancer that’s spread to nearby lymph nodes.
- 38 percent, for cancer that’s spread to other parts of the body.
Overall, 60 percent of all people with oral cancer will survive for five years or more. The earlier the stage at diagnosis, the higher the chance of survival after treatment. In fact, the five-year overall survival rate in those with stage 1 and 2 oral cancers is typically 70 to 90 percent. This makes timely diagnosis and treatment all the more important.
How is oral cancer treated?
Treatment for oral cancer will vary depending on the type, location, and stage of cancer at diagnosis.
Surgery
Treatment for early stages usually involves surgery to remove the tumour and cancerous lymph nodes. In addition, other tissue around the mouth and neck may be taken out.
Radiation therapy
Radiation therapy is another option. This involves a doctor aiming radiation beams at the tumour once or twice a day, five days a week, for two to eight weeks. Treatment for advanced stages will usually involve a combination of chemotherapy and radiation therapy.
Chemotherapy
Chemotherapy is a treatment with drugs that kill cancer cells. The medicine is given to you either orally or through an intravenous (IV) line. Most people get chemotherapy on an outpatient basis, although some require hospitalization.
Targeted therapy
Targeted therapy is another form of treatment. It can be effective in both the early and advanced stages of cancer. Targeted therapy drugs will bind to specific proteins on cancer cells and interfere with their growth.
Nutrition
Nutrition is also an important part of your oral cancer treatment. Many treatments make it difficult or painful to eat and swallow, and poor appetite and weight loss are common. Make sure you discuss your diet with your doctor.
Getting the advice of a nutritionist can help you plan a food menu that will be gentle on your mouth and throat and will provide your body with the calories, vitamins, and minerals it needs to heal.
Keeping your mouth healthy
Finally, keeping your mouth healthy during cancer treatments is a crucial part of treatment. Make sure to keep your mouth moist and your teeth and gums clean.
Recovering from oral cancer treatment
The recovery from each type of treatment will vary. Post Surgery symptoms can include pain and swelling, but removing small tumours usually has no associated long-term problems.
The removal of larger tumours could possibly affect your ability to chew, swallow, or talk as well as you did before the surgery. You might also need reconstructive surgery to rebuild the bones and tissues in your face removed during surgery.
Radiation therapy can have a negative effect on the body. Some of the side effects of radiation include:
- a sore throat or mouth.
- dry mouth and loss of salivary gland function.
- tooth decay.
- nausea and vomiting.
- sore or bleeding gums.
- skin and mouth infections.
- jaw stiffness and pain.
- problems wearing dentures.
- fatigue.
- a change in your ability to taste and smell
- changes in your skin, including dryness and burning.
- weight loss.
- thyroid changes.
Chemotherapy drugs can be toxic to rapidly grow non-cancerous cells. This can cause side effects such as:
- hair loss.
- painful mouth and gums.
- bleeding in the mouth.
- severe anaemia.
- weakness.
- poor appetite.
- nausea.
- vomiting.
- diarrhoea.
- mouth and lip sores.
- numbness in the hands and feet.
Recovering from targeted therapies is usually minimal. The side effects of this treatment can include:
- fever.
- headache.
- vomiting.
- diarrhea.
- an allergic reaction.